Intra Cytoplasmic Sperm Injection (ICSI)

It is an assisted reproductive technology wherein a single sperm is injected into a healthy egg for fertilization.

Unexplained fertilization failure in an IVF cycle
Low sperm count
Decreased sperm motility, including totally immotile sperm
An unusually high percentage of morphologically abnormal sperm, including round-headed sperm (globozoospermia)
Obstructive azoospermia
Absence of sperm in the ejaculate due to defective sperm production (non-obstructive azoospermia)
Ejaculatory dysfunction
Immunological factors; anti-sperm antibodies in female sera, follicular fluid, or on sperm caused by vasectomy or genital tract infection
Testicular cancer patients with semen samples frozen prior to treatment

The doctor places the egg on a lab dish using a pipette.

A single sperm is immobilized and picked up via a thin needle.

This needle is inserted into the egg to reach the cytoplasm.

The sperm is injected into the cytoplasm.

The needle is withdrawn from the egg.

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